It's All About The Funnies:
Here's my vote in no particular order:
Luann
For Better or For Worse
Peanuts (sentimental reasons)
Non-Sequitur
Doonesbury
Tank McNamara
Shoe
Dilbert
Foxtrot (I'm familiar with this from The Freep- it's pretty good)
Big Top (wanted to vote for something new, "Buckles" and "Grand Avenue" looked OK, too)